CME: Addressing Insomnia in Patients with Alzheimer’s Disease

Addressing Insomnia in Patients with Alzheimer’s Disease

Addressing Insomnia in Patients with Alzheimer’s Disease

Not only is the insomnia of Alzheimer’s difficult to manage, but it may also impact the normal functioning of the brain’s glymphatic system.

Available credits: 0.50

Time to complete: 30 Minutes


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  • Overview

    Patients with Alzheimer’s disease can exhibit increasingly severe sleep disturbances as their disease progresses. Not only is the insomnia of Alzheimer’s complex to manage, the sleep disturbance(s) may impact the normal functioning of the brain glymphatic system, potentially resulting in the accumulation of amyloid and/or tau in the brain.

    This educational activity discusses this new view of insomnia and Alzheimer’s disease and provides guidance on non-pharmacologic and pharmacologic approaches to managing the burden of insomnia.  

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Commercial Support, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. GLC resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs. 


    Richard S. Isaacson, MD
    Associate Professor of Neurology
    Weill Cornell Medical College
    Cornell University
    Associate Attending Neurologist
    New York-Presbyterian Hospital
    New York, New York

    No relationship reported.

    David N. Neubauer, MD
    Associate Professor
    Johns Hopkins University School of Medicine
    Baltimore, MD

    Consulting Fees: Eisai US
    Speakers Bureau: Abbott Labs

    Reviewers/Content Planners/Authors:

    • Ann Early has nothing to disclose.
    • Barry A. Fiedel, PhD has nothing to disclose.
    • Nick Lombardi has ownership interest in Vertex Pharmaceuticals.
    • Jessica McGrory has nothing to disclose.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Demonstrate an understanding of the pathophysiologic relationship between insomnia and patients with Alzheimer’s Disease
    • Formulate approaches to manage the sleep disturbances associated with Alzheimer’s disease
  • Target Audience

    This activity is designed to meet the educational needs of Geriatricians, PCPs, Neurologists, and Psychiatrists.

  • Accreditation and Credit Designation Statements

    Global Learning Collaborative is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

    Global Learning Collaborative designates this enduring material for a maximum of .50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    Prova Education, designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties. 

    Prova Education's methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the very best education in the most impactful manner and to verify its results with progressive outcomes research.  

  • Commercial Support

    This activity is supported by an independent educational grant from Merck.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Reproduction Prohibited

    Reproduction of this material is not permitted without written permission from the copyright owner.

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